2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-122542A
    PPACK dihydrochloride 82188-90-7 98%
    PPACK dihydrochloride is potent, selective and irreversible thrombin inhibitor. PPACK dihydrochloride can be used an alternative anticoagulant to lithium heparin (LiHep) for blood gas and whole-blood electrolyte analyses. PPACK dihydrochloride is also a plasminogen activator (rt-PA) inhibitor. PPACK dihydrochloride can inhibit the binding of rt-PA to plasma protease inhibitors.
    PPACK dihydrochloride
  • HY-122543A
    PPACK II 74392-49-7 98%
    PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor.
    PPACK II
  • HY-122778R
    δ-Tocotrienol (Standard) 25612-59-3
    δ-Tocotrienol (Standard) is the analytical standard of δ-Tocotrienol. This product is intended for research and analytical applications. δ-Tocotrienol is a Vitamin E in vegetables, fruits, seeds, nuts, grains and oils. Vitamin E has become well known for its role as an antioxidant, in lowering cholesterol and other lipids, as a neuroprotective and anticancer agent, and in cardiovascular disease protection.
    δ-Tocotrienol (Standard)
  • HY-122792R
    Phenyramidol Hydrochloride (Standard) 326-43-2
    Phenyramidol (Hydrochloride) (Standard) is the analytical standard of Phenyramidol (Hydrochloride). This product is intended for research and analytical applications. Phenyramidol hydrochloride is an anticoagulant and analgesic with activity that increases detection sensitivity in biological samples. Phenyramidol hydrochloride can be oxidized in aqueous media by electrochemical methods to achieve its quantitative analysis. The detection of Phenyramidol hydrochloride using an amino-functionalized multi-walled carbon nanotube-modified glassy carbon electrode showed significant enhancement of the current peak.
    Phenyramidol Hydrochloride (Standard)
  • HY-123400A
    iso-Samixogrel 133276-52-5 98%
    Iso-Samixogrel (iso-DTTX30) is a combined thromboxane A2 receptor blocker and thromboxane synthetase inhibitor that exhibits potent antithrombotic activity. Iso-Samixogrel effectively eliminates recurrent arterial thrombus formation and inhibits collagen-induced platelet aggregation ex vivo. Iso-Samixogrel also prolongs sublingual bleeding time, demonstrating its biological efficacy in managing thrombosis.
    iso-Samixogrel
  • HY-123449A
    MK-761 TFA 99.93%
    MK-761 TFA is a potent and orally active β2-adrenergic blocker. MK-761 TFA shows antihypertensive and positive inotropic effects. MK-761 TFA shows vasodilating properties.
    MK-761 TFA
  • HY-125101A
    Rafutrombopag diolamine 1257792-42-9 98%
    Rafutrombopag diolamine is the derivative of Rafutrombopag. Rafutrombopag is a thrombopoietin receptor agonist.
    Rafutrombopag diolamine
  • HY-125643R
    Pitavastatin lactone (Standard) 141750-63-2
    Tobramycin (Standard) is the analytical standard of Tobramycin. This product is intended for research and analytical applications. Tobramycin (Nebramycin Factor 6) is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms.Tobramycin can be used to pneumonia research caused by Pseudomonas aeruginosa.
    Pitavastatin lactone (Standard)
  • HY-125665R
    Pheophorbide A (Standard) 15664-29-6
    Xanthinol Nicotinate (Standard) is the analytical standard of Xanthinol Nicotinate. This product is intended for research and analytical applications. Xanthinol Nicotinate (Xanthinol Niacinate), a vasodilator, can act directly on the smooth muscle of small arteries and capillaries. Xanthinol Nicotinate expands blood vessels, improves blood rheology and reduces peripheral vascular resistance.
    Pheophorbide A (Standard)
  • HY-125780R
    5-Phenylhydantoin (Standard) 89-24-7
    Dasatinib (monohydrate) (Standard) is the analytical standard of Dasatinib (monohydrate). This product is intended for research and analytical applications. Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib monohydrate also induces apoptosis and autophagy.
    5-Phenylhydantoin (Standard)
  • HY-125856A
    Milvexian TFA 1802426-00-1 98%
    Milvexian TFA (BMS-986177 TFA) is a factor XIa inhibitor with biological activity to prevent venous thromboembolism. Milvexian TFA was effective in reducing the occurrence of venous thromboembolism in patients undergoing knee replacement surgery. Milvexian TFA has good selectivity and shows significant inhibitory effects on plasma kallikrein and trypsin. Milvexian TFA has a bioavailability of 32%, which means it has a high absorption rate in the body. Milvexian TFA showed a relatively low risk of bleeding in clinical trials.
    Milvexian TFA
  • HY-125863B
    Glucose 6-phosphate dehydrogenase (yeast, recombinant) 9001-40-5 98%
    Glucose 6-phosphate dehydrogenase (yeast, recombinant) is the rate-limiting enzyme of the pentose phosphate pathway and a major source of NADPH in antioxidant pathways, nitric oxide synthase, NADPH oxidase, and cytochrome P450 systems. Glucose 6-phosphate dehydrogenase helps cells resist oxidative stress and regulates metabolic rates. It holds potential for research in fields such as diabetes, endothelial dysfunction, cancer, and cardiomyopathy.
    Glucose 6-phosphate dehydrogenase (yeast, recombinant)
  • HY-125864A
    Canine Fibrinogen 9001-32-5 98%
    Canine Fibrinogen is a native fibrinogen from canine plasma.
    Canine Fibrinogen
  • HY-125864B
    Murine Fibrinogen 9001-32-5 98%
    Murine Fibrinogen is a native fibrinogen from murine plasma.
    Murine Fibrinogen
  • HY-125864C
    Porcine Fibrinogen 9001-32-5 98%
    Porcine Fibrinogen is a native fibrinogen from porcine plasma.
    Porcine Fibrinogen
  • HY-125864D
    Rabbit Fibrinogen 9001-32-5 98%
    Rabbit Fibrinogen is a native fibrinogen from rabbit plasma.
    Rabbit Fibrinogen
  • HY-125911R
    Gossypin (Standard) 652-78-8
    Gossypin (Standard) is the analytical standard of Gossypin. This product is intended for research and analytical applications. Gossypin is an orally active flavone isolated from Hibiscus vitifolius. Gossypin has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits AURKA and RSK2. Gossypin inhibits invasion and induces apoptosis. Gossypin can be used for gastric cancer study.
    Gossypin (Standard)
  • HY-126028A
    (+)-Sotalol 30236-32-9 98.82%
    (+)-Sotalol ((S)-Sotalol) is the S-isomer of Sotalol (HY-103196). Sotalol is an orally active, non-selective β-adrenergic receptor blocker. (+)-Sotalol is an antiarrhythmic agent. (+)-Sotalol can prolong action potential duration in isolated cardiac muscle.
    (+)-Sotalol
  • HY-126562R
    Piperlonguminine (Standard) 5950-12-9
    Sotalol (hydrochloride) (Standard) is the analytical standard of Sotalol (hydrochloride). This product is intended for research and analytical applications. Sotalol hydrochloride (MJ 1999) is an orally active, non-selective β-adrenergic receptor blocker. Sotalol hydrochloride is a potent antiarrhythmic agent that can be used for the research of pediatric arrhythmias. Sotalol hydrochloride blocks β-receptors, and potassium KCNH2 channels. Antiepileptic Agent.
    Piperlonguminine (Standard)
  • HY-127026A
    Quinaprilat hydrate 1435786-09-6 98%
    Quinaprilat hydrate is a non-mercapto Angiotensin Converting Enzyme (ACE) inhibitor, the active metabolite of Quinapril. Quinaprilat hydrate specifically blocks the conversion of angiotensin I to the vasoconstrictor angiotensin II and inhibits the degradation of bradykinin. Quinaprilat hydrate acts as anti-hypertensive agent and vasodilator.
    Quinaprilat hydrate
Cat. No. Product Name / Synonyms Application Reactivity